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Gene knockdown by structure defined single-stem loop small non-coding RNAs with programmable regulatory activities
Gene regulation by trans-acting small RNAs (sRNAs) has considerable advantages over other gene regulation strategies. However, synthetic sRNAs mainly take natural sRNAs (MicC or SgrS) as backbones and comprise three functional elements folding into two or more stem-loop structures: an mRNA base pair...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761848/ https://www.ncbi.nlm.nih.gov/pubmed/36582457 http://dx.doi.org/10.1016/j.synbio.2022.11.006 |