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Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
The long-lived Chilean rodent (Octodon degus) has been reported to show spontaneous age-dependent neuropathology and cognitive impairments similar to those observed in human AD. However, the handful of published papers on degus of differing genetic backgrounds yield inconsistent findings about spora...
Autores principales: | Tan, Zhiqun, Garduño, B. Maximiliano, Aburto, Pedro Fernández, Chen, Lujia, Ha, Nicole, Cogram, Patricia, Holmes, Todd C., Xu, Xiangmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761982/ https://www.ncbi.nlm.nih.gov/pubmed/36529803 http://dx.doi.org/10.1186/s40478-022-01481-x |
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