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Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

The long-lived Chilean rodent (Octodon degus) has been reported to show spontaneous age-dependent neuropathology and cognitive impairments similar to those observed in human AD. However, the handful of published papers on degus of differing genetic backgrounds yield inconsistent findings about spora...

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Detalles Bibliográficos
Autores principales: Tan, Zhiqun, Garduño, B. Maximiliano, Aburto, Pedro Fernández, Chen, Lujia, Ha, Nicole, Cogram, Patricia, Holmes, Todd C., Xu, Xiangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761982/
https://www.ncbi.nlm.nih.gov/pubmed/36529803
http://dx.doi.org/10.1186/s40478-022-01481-x

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