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A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity
The blood-brain barrier (BBB) restricts paracellular and transcellular diffusion of compounds and is part of a dynamic multicellular structure known as the “neurovascular unit” (NVU), which strictly regulates the brain homeostasis and microenvironment. Several neuropathological conditions (e.g., Par...
Autores principales: | Barberio, Chiara, Withers, Aimee, Mishra, Yash, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Owens, Róisín M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762047/ https://www.ncbi.nlm.nih.gov/pubmed/36545654 http://dx.doi.org/10.3389/fncel.2022.1065193 |
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