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Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes

BACKGROUND: Amongst risk alleles associated with late-onset Alzheimer’s disease (AD), those that converged on the regulation of microglia activity have emerged as central to disease progression. Yet, how canonical amyloid-β (Aβ) and tau pathologies regulate microglia subtypes during the progression...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Won, Tu, Kevin J., Wei, Alice, Lau, Ashley J., Gonzalez-Gil, Anabel, Cao, Tianyu, Braunstein, Kerstin, Ling, Jonathan P., Troncoso, Juan C., Wong, Philip C., Blackshaw, Seth, Schnaar, Ronald L., Li, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762062/ https://www.ncbi.nlm.nih.gov/pubmed/36536457 http://dx.doi.org/10.1186/s13024-022-00589-x

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