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Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics
Neonatal jaundice is a very common disease in newborns and can lead to brain damage or death in severe cases. Phototherapy with light‐emitting diode (LED) arrays is widely used as the easiest and fastest way to relieve jaundice in newborns, but it has distinct disadvantages such as loss of water in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762290/ https://www.ncbi.nlm.nih.gov/pubmed/36310107 http://dx.doi.org/10.1002/advs.202204622 |
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author | Choi, Seungyeop Jeon, Yongmin Kwon, Jeong Hyun Ihm, Chunhwa Kim, Seung Yeon Choi, Kyung Cheol |
author_facet | Choi, Seungyeop Jeon, Yongmin Kwon, Jeong Hyun Ihm, Chunhwa Kim, Seung Yeon Choi, Kyung Cheol |
author_sort | Choi, Seungyeop |
collection | PubMed |
description | Neonatal jaundice is a very common disease in newborns and can lead to brain damage or death in severe cases. Phototherapy with light‐emitting diode (LED) arrays is widely used as the easiest and fastest way to relieve jaundice in newborns, but it has distinct disadvantages such as loss of water in the patient, damage to the retina, and separation from parents. In this paper, a novel light source‐based phototherapy for neonatal jaundice is proposed using a textile‐based wearable organic light‐emitting diode (OLED) platform that can move flexibly and conform to the curvature of the human body. The soft and flexible textile‐based blue OLED platform is designed to have a peak wavelength of 470 nm, suitable for jaundice treatment, and shows performance (>20 µW cm(−2) nm(−) (1)) suitable for intensive jaundice treatment even at low voltage (<4.0 V). The textile‐based OLEDs fabricated in this study exhibit an operating reliability of over 100 h and low‐temperature operation (<35 °C). The results of an in vitro jaundice treatment test using a large‐area blue OLED confirm that the bilirubin level decreases to 12 mg dL(−1) with 3 h of OLED irradiation. |
format | Online Article Text |
id | pubmed-9762290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97622902022-12-20 Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics Choi, Seungyeop Jeon, Yongmin Kwon, Jeong Hyun Ihm, Chunhwa Kim, Seung Yeon Choi, Kyung Cheol Adv Sci (Weinh) Research Articles Neonatal jaundice is a very common disease in newborns and can lead to brain damage or death in severe cases. Phototherapy with light‐emitting diode (LED) arrays is widely used as the easiest and fastest way to relieve jaundice in newborns, but it has distinct disadvantages such as loss of water in the patient, damage to the retina, and separation from parents. In this paper, a novel light source‐based phototherapy for neonatal jaundice is proposed using a textile‐based wearable organic light‐emitting diode (OLED) platform that can move flexibly and conform to the curvature of the human body. The soft and flexible textile‐based blue OLED platform is designed to have a peak wavelength of 470 nm, suitable for jaundice treatment, and shows performance (>20 µW cm(−2) nm(−) (1)) suitable for intensive jaundice treatment even at low voltage (<4.0 V). The textile‐based OLEDs fabricated in this study exhibit an operating reliability of over 100 h and low‐temperature operation (<35 °C). The results of an in vitro jaundice treatment test using a large‐area blue OLED confirm that the bilirubin level decreases to 12 mg dL(−1) with 3 h of OLED irradiation. John Wiley and Sons Inc. 2022-10-30 /pmc/articles/PMC9762290/ /pubmed/36310107 http://dx.doi.org/10.1002/advs.202204622 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Choi, Seungyeop Jeon, Yongmin Kwon, Jeong Hyun Ihm, Chunhwa Kim, Seung Yeon Choi, Kyung Cheol Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title | Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title_full | Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title_fullStr | Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title_full_unstemmed | Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title_short | Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light‐Emitting Diodes (OLEDs): Toward Textile‐Based Wearable Phototherapeutics |
title_sort | wearable photomedicine for neonatal jaundice treatment using blue organic light‐emitting diodes (oleds): toward textile‐based wearable phototherapeutics |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762290/ https://www.ncbi.nlm.nih.gov/pubmed/36310107 http://dx.doi.org/10.1002/advs.202204622 |
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