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Kartogenin‐Conjugated Double‐Network Hydrogel Combined with Stem Cell Transplantation and Tracing for Cartilage Repair (Adv. Sci. 35/2022)

Cartilage Regeneration PEG‐CHI‐KGN DN gel combined with peripheral blood‐derived mesenchymal stem cells (PB‐MSCs) is employed in treating knee cartilage defects. Compared with current tissue‐engineering products, it has unique strength because of optimized mechanics, high biosafety, and a simple pre...

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Detalles Bibliográficos
Autores principales: Chen, You‐Rong, Yan, Xin, Yuan, Fu‐Zhen, Lin, Lin, Wang, Shao‐Jie, Ye, Jing, Zhang, Ji‐Ying, Yang, Meng, Wu, De‐Cheng, Wang, Xing, Yu, Jia‐Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762310/
http://dx.doi.org/10.1002/advs.202270225
Descripción
Sumario:Cartilage Regeneration PEG‐CHI‐KGN DN gel combined with peripheral blood‐derived mesenchymal stem cells (PB‐MSCs) is employed in treating knee cartilage defects. Compared with current tissue‐engineering products, it has unique strength because of optimized mechanics, high biosafety, and a simple preparation process. PEG‐CHI‐KGN DN gel promote the chondrogenic differentiation and survival of allogenic PB‐MSCs, ultimately enhancing cartilage regeneration and providing an innovative clinical treatment strategy from the tissue‐engineering perspective. More details can be found in article number 2105571 by De‐Cheng Wu, Xing Wang, Jia‐Kuo Yu, and co‐workers. [Image: see text]