An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination

Exercise prevents cancer incidence and recurrence, yet the underlying mechanism behind this relationship remains mostly unknown. Here we report that exercise induces the metabolic reprogramming of internal organs that increases nutrient demand and protects against metastatic colonization by limiting...

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Detalles Bibliográficos
Autores principales: Sheinboim, Danna, Parikh, Shivang, Manich, Paulee, Markus, Irit, Dahan, Sapir, Parikh, Roma, Stubbs, Elisa, Cohen, Gali, Zemser-Werner, Valentina, Bell, Rachel E., Ruiz, Sara Arciniegas, Percik, Ruth, Brenner, Ronen, Leibou, Stav, Vaknine, Hananya, Arad, Gali, Gerber, Yariv, Keinan-Boker, Lital, Shimony, Tal, Bikovski, Lior, Goldstein, Nir, Constantini, Keren, Labes, Sapir, Mordechai, Shimonov, Doron, Hila, Lonescu, Ariel, Ziv, Tamar, Nizri, Eran, Choshen, Guy, Eldar-Finkelman, Hagit, Tabach, Yuval, Helman, Aharon, Ben-Eliyahu, Shamgar, Erez, Neta, Perlson, Eran, Geiger, Tamar, Ben-Zvi, Danny, Khaled, Mehdi, Gepner, Yftach, Levy, Carmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Metabolism and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762351/
https://www.ncbi.nlm.nih.gov/pubmed/36084256
http://dx.doi.org/10.1158/0008-5472.CAN-22-0237

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