Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein

BACKGROUND: Stress responses are believed to involve corticotropin releasing factor (CRF), its two cognate receptors (CRF(1) and CRF(2)), and the CRF-binding protein (CRFBP). Whereas decades of research has focused on CRF(1,) the role of CRF(2) in the central nervous system (CNS) has not been thorou...

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Detalles Bibliográficos
Autores principales: Haass-Koffler, Carolina L., Chase Francis, T., Gandhi, Pauravi, Patel, Reesha, Naemuddin, Mohammad, Nielsen, Carsten K., Bartlett, Selena E., Bonci, Antonello, Vasile, Stefan, Hood, Becky L., Suyama, Eigo, Hedrick, Michael P., Smith, Layton H., Limpert, Allison S., Roberto, Marisa, Cosford, Nicholas D.P., Sheffler, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762412/
https://www.ncbi.nlm.nih.gov/pubmed/36210051
http://dx.doi.org/10.1016/j.slasd.2022.09.005

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