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Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden

The real-time analysis of infectious disease surveillance data is essential in obtaining situational awareness about the current dynamics of a major public health event such as the COVID-19 pandemic. This analysis of e.g., time-series of reported cases or fatalities is complicated by reporting delay...

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Detalles Bibliográficos
Autores principales: Bergström, Fanny, Günther, Felix, Höhle, Michael, Britton, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762573/
https://www.ncbi.nlm.nih.gov/pubmed/36477048
http://dx.doi.org/10.1371/journal.pcbi.1010767
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author Bergström, Fanny
Günther, Felix
Höhle, Michael
Britton, Tom
author_facet Bergström, Fanny
Günther, Felix
Höhle, Michael
Britton, Tom
author_sort Bergström, Fanny
collection PubMed
description The real-time analysis of infectious disease surveillance data is essential in obtaining situational awareness about the current dynamics of a major public health event such as the COVID-19 pandemic. This analysis of e.g., time-series of reported cases or fatalities is complicated by reporting delays that lead to under-reporting of the complete number of events for the most recent time points. This can lead to misconceptions by the interpreter, for instance the media or the public, as was the case with the time-series of reported fatalities during the COVID-19 pandemic in Sweden. Nowcasting methods provide real-time estimates of the complete number of events using the incomplete time-series of currently reported events and information about the reporting delays from the past. In this paper we propose a novel Bayesian nowcasting approach applied to COVID-19-related fatalities in Sweden. We incorporate additional information in the form of time-series of number of reported cases and ICU admissions as leading signals. We demonstrate with a retrospective evaluation that the inclusion of ICU admissions as a leading signal improved the nowcasting performance of case fatalities for COVID-19 in Sweden compared to existing methods.
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spelling pubmed-97625732022-12-20 Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden Bergström, Fanny Günther, Felix Höhle, Michael Britton, Tom PLoS Comput Biol Research Article The real-time analysis of infectious disease surveillance data is essential in obtaining situational awareness about the current dynamics of a major public health event such as the COVID-19 pandemic. This analysis of e.g., time-series of reported cases or fatalities is complicated by reporting delays that lead to under-reporting of the complete number of events for the most recent time points. This can lead to misconceptions by the interpreter, for instance the media or the public, as was the case with the time-series of reported fatalities during the COVID-19 pandemic in Sweden. Nowcasting methods provide real-time estimates of the complete number of events using the incomplete time-series of currently reported events and information about the reporting delays from the past. In this paper we propose a novel Bayesian nowcasting approach applied to COVID-19-related fatalities in Sweden. We incorporate additional information in the form of time-series of number of reported cases and ICU admissions as leading signals. We demonstrate with a retrospective evaluation that the inclusion of ICU admissions as a leading signal improved the nowcasting performance of case fatalities for COVID-19 in Sweden compared to existing methods. Public Library of Science 2022-12-07 /pmc/articles/PMC9762573/ /pubmed/36477048 http://dx.doi.org/10.1371/journal.pcbi.1010767 Text en © 2022 Bergström et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Bergström, Fanny
Günther, Felix
Höhle, Michael
Britton, Tom
Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title_full Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title_fullStr Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title_full_unstemmed Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title_short Bayesian nowcasting with leading indicators applied to COVID-19 fatalities in Sweden
title_sort bayesian nowcasting with leading indicators applied to covid-19 fatalities in sweden
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762573/
https://www.ncbi.nlm.nih.gov/pubmed/36477048
http://dx.doi.org/10.1371/journal.pcbi.1010767
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