Evaluation of antiviral activity of terpenophenols and some of their N- and O-derivatives

A comparative evaluation of the antiviral activity of a number of new and previously synthesized terpenophenols and their N- or O-containing derivatives against the A/Puerto Rico/8/34 (H1N1) virus strain was carried out. 2-Isobornylphenol, 1,2-dihydroxy-6-isobornyl-4-methylbenzene, 2-isobornyl-1,4-b...

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Detalles Bibliográficos
Autores principales: Chukicheva, I. Yu., Buravlev, E. V., Dvornikova, I. A., Fedorova, I. V., Zarubaev, V. V., Slita, A. V., Esaulkova, Ya. L., Kutchin, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762639/
https://www.ncbi.nlm.nih.gov/pubmed/36569656
http://dx.doi.org/10.1007/s11172-022-3676-y
Descripción
Sumario:A comparative evaluation of the antiviral activity of a number of new and previously synthesized terpenophenols and their N- or O-containing derivatives against the A/Puerto Rico/8/34 (H1N1) virus strain was carried out. 2-Isobornylphenol, 1,2-dihydroxy-6-isobornyl-4-methylbenzene, 2-isobornyl-1,4-benzoquinone, and N-butyl-4-hydroxy-3,5-diisobornylbenzamide showed the highest activity.

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