4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics

A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.

Detalles Bibliográficos
Autores principales: Drokin, R. A., Fesenko, E. A., Mozharovskaia, P. N., Medvedeva, M. V., Svalova, T. S., Kozitsina, A. N., Esaulkova, Ya. L., Volobueva, A. S., Zarubaev, V. V., Rusinov, V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Full Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/
https://www.ncbi.nlm.nih.gov/pubmed/36569657
http://dx.doi.org/10.1007/s11172-022-3674-0
Descripción
Sumario:A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.

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