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4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/ https://www.ncbi.nlm.nih.gov/pubmed/36569657 http://dx.doi.org/10.1007/s11172-022-3674-0 |
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author | Drokin, R. A. Fesenko, E. A. Mozharovskaia, P. N. Medvedeva, M. V. Svalova, T. S. Kozitsina, A. N. Esaulkova, Ya. L. Volobueva, A. S. Zarubaev, V. V. Rusinov, V. L. |
author_facet | Drokin, R. A. Fesenko, E. A. Mozharovskaia, P. N. Medvedeva, M. V. Svalova, T. S. Kozitsina, A. N. Esaulkova, Ya. L. Volobueva, A. S. Zarubaev, V. V. Rusinov, V. L. |
author_sort | Drokin, R. A. |
collection | PubMed |
description | A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied. |
format | Online Article Text |
id | pubmed-9762649 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-97626492022-12-20 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics Drokin, R. A. Fesenko, E. A. Mozharovskaia, P. N. Medvedeva, M. V. Svalova, T. S. Kozitsina, A. N. Esaulkova, Ya. L. Volobueva, A. S. Zarubaev, V. V. Rusinov, V. L. Russ Chem Bull Full Articles A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied. Springer US 2022-12-19 2022 /pmc/articles/PMC9762649/ /pubmed/36569657 http://dx.doi.org/10.1007/s11172-022-3674-0 Text en © Springer Science+Business Media LLC 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Full Articles Drokin, R. A. Fesenko, E. A. Mozharovskaia, P. N. Medvedeva, M. V. Svalova, T. S. Kozitsina, A. N. Esaulkova, Ya. L. Volobueva, A. S. Zarubaev, V. V. Rusinov, V. L. 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title | 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title_full | 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title_fullStr | 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title_full_unstemmed | 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title_short | 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
title_sort | 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics |
topic | Full Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/ https://www.ncbi.nlm.nih.gov/pubmed/36569657 http://dx.doi.org/10.1007/s11172-022-3674-0 |
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