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4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics

A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.

Detalles Bibliográficos
Autores principales: Drokin, R. A., Fesenko, E. A., Mozharovskaia, P. N., Medvedeva, M. V., Svalova, T. S., Kozitsina, A. N., Esaulkova, Ya. L., Volobueva, A. S., Zarubaev, V. V., Rusinov, V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/
https://www.ncbi.nlm.nih.gov/pubmed/36569657
http://dx.doi.org/10.1007/s11172-022-3674-0
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author Drokin, R. A.
Fesenko, E. A.
Mozharovskaia, P. N.
Medvedeva, M. V.
Svalova, T. S.
Kozitsina, A. N.
Esaulkova, Ya. L.
Volobueva, A. S.
Zarubaev, V. V.
Rusinov, V. L.
author_facet Drokin, R. A.
Fesenko, E. A.
Mozharovskaia, P. N.
Medvedeva, M. V.
Svalova, T. S.
Kozitsina, A. N.
Esaulkova, Ya. L.
Volobueva, A. S.
Zarubaev, V. V.
Rusinov, V. L.
author_sort Drokin, R. A.
collection PubMed
description A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.
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spelling pubmed-97626492022-12-20 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics Drokin, R. A. Fesenko, E. A. Mozharovskaia, P. N. Medvedeva, M. V. Svalova, T. S. Kozitsina, A. N. Esaulkova, Ya. L. Volobueva, A. S. Zarubaev, V. V. Rusinov, V. L. Russ Chem Bull Full Articles A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied. Springer US 2022-12-19 2022 /pmc/articles/PMC9762649/ /pubmed/36569657 http://dx.doi.org/10.1007/s11172-022-3674-0 Text en © Springer Science+Business Media LLC 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Full Articles
Drokin, R. A.
Fesenko, E. A.
Mozharovskaia, P. N.
Medvedeva, M. V.
Svalova, T. S.
Kozitsina, A. N.
Esaulkova, Ya. L.
Volobueva, A. S.
Zarubaev, V. V.
Rusinov, V. L.
4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title_full 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title_fullStr 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title_full_unstemmed 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title_short 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
title_sort 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics
topic Full Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/
https://www.ncbi.nlm.nih.gov/pubmed/36569657
http://dx.doi.org/10.1007/s11172-022-3674-0
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