Cargando…

4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics

A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.

Detalles Bibliográficos
Autores principales:	Drokin, R. A., Fesenko, E. A., Mozharovskaia, P. N., Medvedeva, M. V., Svalova, T. S., Kozitsina, A. N., Esaulkova, Ya. L., Volobueva, A. S., Zarubaev, V. V., Rusinov, V. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Full Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762649/ https://www.ncbi.nlm.nih.gov/pubmed/36569657 http://dx.doi.org/10.1007/s11172-022-3674-0

Ejemplares similares

Methods of Synthesis and Antiviral Activity of New 4-Alkyl-3-Nitro-1,4-Dihydroazolo[5,1-c][1,2,4]Triazin-4-ols
por: Drokin, Roman A., et al.
Publicado: (2021)

Redox Conversions of 5-Methyl-6-nitro-7-oxo-4,7-dihydro-1,2,4triazolo[1,5-a]pyrimidinide L-Arginine Monohydrate as a Promising Antiviral Drug
por: Ivoilova, Alexandra, et al.
Publicado: (2021)

Xanthone-1,2,4-triazine and Acridone-1,2,4-triazine Conjugates: Synthesis and Anticancer Activity
por: Santra, Sougata, et al.
Publicado: (2023)

Isoxazolyl-Derived 1,4-Dihydroazolo[5,1-c][1,2,4]Triazines: Synthesis and Photochemical Properties
por: Sadchikova, Elena V., et al.
Publicado: (2023)

Novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine and [1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine Derivatives: Synthesis, Anti-Viral In Vitro Study and Target Validation Activity
por: Khramchikhin, Andrey V., et al.
Publicado: (2022)

Crystal Structure Analysis of 4-Oxo, 4-hydroxy- and 4-alkyl-7-bromopyrazolo[5,1-c][1,2,4]triazines
por: Ivanov, Sergey M., et al.
Publicado: (2022)

7-Imidazolyl-substituted 4'-methoxy and 3',4'-dimethoxy-containing polyfluoroflavones as promising antiviral agents
por: Shcherbakov, Konstantin V., et al.
Publicado: (2020)

CRYSTAL STRUCTURE OF 3-tert-BUTYL- PYRAZOLO[5,1-с][1,2,4]TRIAZINE-3,4-DIYL DICARBOXYLATES
por: Mironovich, L. M., et al.
Publicado: (2021)

Strain-Promoted Reaction of 1,2,4-Triazines with Bicyclononynes
por: Horner, Katherine A, et al.
Publicado: (2015)

Revisiting the Synthesis of Functionally Substituted 1,4-Dihydrobenzo[e][1,2,4]triazines
por: Epishina, Margarita A., et al.
Publicado: (2022)

Efficient Routes to Pyrazolo[3,4-e][1,2,4]triazines and a New Ring System: [1,2,4]Triazino[5,6-d][1,2,3]triazines
por: Al-Matar, Hamad Mohamed, et al.
Publicado: (2010)

Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1-c][1,2,4]triazolo[3,4-f][1,2,4]triazines
por: El Azab, Islam H., et al.
Publicado: (2020)

Synthesis, biological activity and molecular modeling study of novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines
por: El-Reedy, Ahmed A. M., et al.
Publicado: (2020)

Synthesis and crystal structures of 7,8-bromo (dibromo)-3-tert-butylpyrazolo[5,1-c][1,2,4]triazines
por: Ivanov, Sergey M., et al.
Publicado: (2021)

Novel 1,2,4-Triazole- and Tetrazole-Containing 4H-Thiopyrano[2,3-b]quinolines: Synthesis Based on the Thio-Michael/aza-Morita–Baylis–Hillman Tandem Reaction and Investigation of Antiviral Activity
por: Khramchikhin, Andrey V., et al.
Publicado: (2023)

5,6-Dimethyl-1,2,4-triazin-3-amine
por: Wu, Man-Hua, et al.
Publicado: (2011)

3-Methylsulfanyl-5-phenyl-1,2,4-triazine
por: Hamri, Salha, et al.
Publicado: (2014)

2-Phenyl-7-(4-pyridylmethylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5(4H)-one
por: Dolzhenko, Anton V., et al.
Publicado: (2010)

The Suppression of Columnar π-Stacking in 3-Adamantyl-1-phenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl
por: Constantinides, Christos P., et al.
Publicado: (2016)

Regio- and Diastereoselective 1,3-Dipolar Cycloadditions of 1,2,4-Triazin-1-ium Ylides: a Straightforward Synthetic Route to Polysubstituted Pyrrolo[2,1-f][1,2,4]triazines
por: Galeta, Juraj, et al.
Publicado: (2022)

Synthesis of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via a base-induced rearrangement of functionalized imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazines
por: Vinogradov, Dmitry B, et al.
Publicado: (2023)

The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions
por: Siegl, Sebastian J., et al.
Publicado: (2017)

Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer
por: Hermanowicz, Justyna Magdalena, et al.
Publicado: (2021)

Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)
por: Batova, Monika, et al.
Publicado: (2010)

7-(4-Fluorobenzylamino)-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol disolvate
por: Dolzhenko, Anton V., et al.
Publicado: (2011)

Design of 4-Substituted Sulfonamidobenzoic Acid Derivatives Targeting Coxsackievirus B3
por: Shetnev, Anton A., et al.
Publicado: (2022)

Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3-e][1,2,4]triazine Derivatives
por: Bernat, Zofia, et al.
Publicado: (2020)

Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir
por: Roy, Sarabindu, et al.
Publicado: (2022)

Tris(3-amino-5,6-dimethyl-1,2,4-triazine-κN (2))silver(I) trifluromethanesulfonate–3-amino-5,6-dimethyl-1,2,4-triazine (1/1)
por: Jiang, Yu-Hang, et al.
Publicado: (2011)

1,3-Dimethyl-5-methylsulfonyl-1H-pyrazolo[4,3-e][1,2,4]triazine
por: Mojzych, Mariusz, et al.
Publicado: (2010)

Mechanism, Kinetics and Thermodynamics of Decomposition for High Energy Derivatives of [1,2,4]Triazolo[4,3-b][1,2,4,5]tetrazine
por: Stankevich, Aleksandr V., et al.
Publicado: (2022)

5,6-Diphenyl-3-(3-pyridyl)-1,2,4-triazine
por: Jian, Fang-Fang, et al.
Publicado: (2010)

2-(5,6-Diphenyl-1,2,4-triazin-3-yl)aniline
por: Mojzych, Mariusz, et al.
Publicado: (2012)

First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions Thereof
por: Bokor, Éva, et al.
Publicado: (2022)

Synthesis of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines and investigation of their fungistatic activity
por: Korotina, Anna V, et al.
Publicado: (2022)

Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region
por: Mojzych, Mariusz, et al.
Publicado: (2005)

Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives.
por: El-Agrody, A.M., et al.
Publicado: (2001)

3-Nitrophenol–1,3,5-triazine-2,4,6-triamine (2/1)
por: Sangeetha, V., et al.
Publicado: (2013)

3,5-Diamino-1-phenyl-1,2,4-triazolium bromide
por: Chernyshev, V. M., et al.
Publicado: (2010)

3-Amino-5,6-dimethyl-1,2,4-triazin-2-ium nitrate
por: Bel Haj Salah, Souhir, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_r9ome7ru80jeb8npsu28sontpl