Genetic Pathways Underlying Individual Differences in Regular Physical Activity

Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoym...

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Detalles Bibliográficos
Autor principal: de Geus, Eco J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Perspective for Progress
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762726/
https://www.ncbi.nlm.nih.gov/pubmed/36044740
http://dx.doi.org/10.1249/JES.0000000000000305
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author de Geus, Eco J.C.
author_facet de Geus, Eco J.C.
author_sort de Geus, Eco J.C.
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description Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.
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spelling pubmed-97627262022-12-20 Genetic Pathways Underlying Individual Differences in Regular Physical Activity de Geus, Eco J.C. Exerc Sport Sci Rev Perspective for Progress Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs. Lippincott Williams & Wilkins 2023-01 2022-09-01 /pmc/articles/PMC9762726/ /pubmed/36044740 http://dx.doi.org/10.1249/JES.0000000000000305 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Sports Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective for Progress
de Geus, Eco J.C.
Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title_full Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title_fullStr Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title_full_unstemmed Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title_short Genetic Pathways Underlying Individual Differences in Regular Physical Activity
title_sort genetic pathways underlying individual differences in regular physical activity
topic Perspective for Progress
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762726/
https://www.ncbi.nlm.nih.gov/pubmed/36044740
http://dx.doi.org/10.1249/JES.0000000000000305
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