High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase

Ceramide has a key role in the regulation of cellular senescence and apoptosis. As Ceramide levels are lowered by the action of acid ceramidase (AC), abnormally expressed in various cancers, the identification of AC inhibitors has attracted increasing interest. However, this finding has been mainly...

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Detalles Bibliográficos
Autores principales: Aseeri, Mazen, Abad, José Luis, Delgado, Antonio, Fabriàs, Gemma, Triola, Gemma, Casas, Josefina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762759/
https://www.ncbi.nlm.nih.gov/pubmed/36519337
http://dx.doi.org/10.1080/14756366.2022.2150183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762759/
https://www.ncbi.nlm.nih.gov/pubmed/36519337
http://dx.doi.org/10.1080/14756366.2022.2150183

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