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Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report invol...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762860/ https://www.ncbi.nlm.nih.gov/pubmed/36545167 http://dx.doi.org/10.7759/cureus.31676 |
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author | De Sousa Machado, André Silva, Ana Brandao, Jose Meireles, Luis |
author_facet | De Sousa Machado, André Silva, Ana Brandao, Jose Meireles, Luis |
author_sort | De Sousa Machado, André |
collection | PubMed |
description | Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report involves a 56-year-old man who exhibited a skin lesion on the nasal dorsum with a mass in the right maxillary sinus. The biopsies from both sides were diagnostic for Merkel cell carcinoma. The patient underwent endoscopic sinus surgery and removal of the skin lesion with free margins. The patient has been free of disease for the last 20 months now and maintains follow-up with endoscopy and imaging in the Ear Nose Throat office. Only a few cases of Merkel cell carcinoma of the nasal mucosa have been reported in the literature. We report our approach and management of this rare pathologic presentation. |
format | Online Article Text |
id | pubmed-9762860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-97628602022-12-20 Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass De Sousa Machado, André Silva, Ana Brandao, Jose Meireles, Luis Cureus Dermatology Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report involves a 56-year-old man who exhibited a skin lesion on the nasal dorsum with a mass in the right maxillary sinus. The biopsies from both sides were diagnostic for Merkel cell carcinoma. The patient underwent endoscopic sinus surgery and removal of the skin lesion with free margins. The patient has been free of disease for the last 20 months now and maintains follow-up with endoscopy and imaging in the Ear Nose Throat office. Only a few cases of Merkel cell carcinoma of the nasal mucosa have been reported in the literature. We report our approach and management of this rare pathologic presentation. Cureus 2022-11-19 /pmc/articles/PMC9762860/ /pubmed/36545167 http://dx.doi.org/10.7759/cureus.31676 Text en Copyright © 2022, De Sousa Machado et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology De Sousa Machado, André Silva, Ana Brandao, Jose Meireles, Luis Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title | Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title_full | Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title_fullStr | Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title_full_unstemmed | Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title_short | Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass |
title_sort | merkel cell carcinoma: an otolaryngological point of view of an unusual sinonasal mass |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762860/ https://www.ncbi.nlm.nih.gov/pubmed/36545167 http://dx.doi.org/10.7759/cureus.31676 |
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