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Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass

Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report invol...

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Autores principales: De Sousa Machado, André, Silva, Ana, Brandao, Jose, Meireles, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762860/
https://www.ncbi.nlm.nih.gov/pubmed/36545167
http://dx.doi.org/10.7759/cureus.31676
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author De Sousa Machado, André
Silva, Ana
Brandao, Jose
Meireles, Luis
author_facet De Sousa Machado, André
Silva, Ana
Brandao, Jose
Meireles, Luis
author_sort De Sousa Machado, André
collection PubMed
description Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report involves a 56-year-old man who exhibited a skin lesion on the nasal dorsum with a mass in the right maxillary sinus. The biopsies from both sides were diagnostic for Merkel cell carcinoma. The patient underwent endoscopic sinus surgery and removal of the skin lesion with free margins. The patient has been free of disease for the last 20 months now and maintains follow-up with endoscopy and imaging in the Ear Nose Throat office. Only a few cases of Merkel cell carcinoma of the nasal mucosa have been reported in the literature. We report our approach and management of this rare pathologic presentation.
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spelling pubmed-97628602022-12-20 Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass De Sousa Machado, André Silva, Ana Brandao, Jose Meireles, Luis Cureus Dermatology Merkel cell carcinoma is a pathologic diagnosis mainly observed in sun-exposed cutaneous areas, like the head and neck. Ultraviolet (UV) exposure and immunosuppression are the common predisposing factors. Merkel cell carcinoma of the head and neck is quite an uncommon disease. This case report involves a 56-year-old man who exhibited a skin lesion on the nasal dorsum with a mass in the right maxillary sinus. The biopsies from both sides were diagnostic for Merkel cell carcinoma. The patient underwent endoscopic sinus surgery and removal of the skin lesion with free margins. The patient has been free of disease for the last 20 months now and maintains follow-up with endoscopy and imaging in the Ear Nose Throat office. Only a few cases of Merkel cell carcinoma of the nasal mucosa have been reported in the literature. We report our approach and management of this rare pathologic presentation. Cureus 2022-11-19 /pmc/articles/PMC9762860/ /pubmed/36545167 http://dx.doi.org/10.7759/cureus.31676 Text en Copyright © 2022, De Sousa Machado et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
De Sousa Machado, André
Silva, Ana
Brandao, Jose
Meireles, Luis
Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title_full Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title_fullStr Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title_full_unstemmed Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title_short Merkel Cell Carcinoma: An Otolaryngological Point of View of An Unusual Sinonasal Mass
title_sort merkel cell carcinoma: an otolaryngological point of view of an unusual sinonasal mass
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762860/
https://www.ncbi.nlm.nih.gov/pubmed/36545167
http://dx.doi.org/10.7759/cureus.31676
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