Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci

Parkinson’s disease is a common incurable neurodegenerative disease. The identification of genetic variants via genome-wide association studies has considerably advanced our understanding of the Parkinson’s disease genetic risk. Understanding the functional significance of the risk loci is now a cri...

Descripción completa

Detalles Bibliográficos
Autores principales: Soutar, Marc P M, Melandri, Daniela, O’Callaghan, Benjamin, Annuario, Emily, Monaghan, Amy E, Welsh, Natalie J, D’Sa, Karishma, Guelfi, Sebastian, Zhang, David, Pittman, Alan, Trabzuni, Daniah, Verboven, Anouk H A, Pan, Kylie S, Kia, Demis A, Bictash, Magda, Gandhi, Sonia, Houlden, Henry, Cookson, Mark R, Kasri, Nael Nadif, Wood, Nicholas W, Singleton, Andrew B, Hardy, John, Whiting, Paul J, Blauwendraat, Cornelis, Whitworth, Alexander J, Manzoni, Claudia, Ryten, Mina, Lewis, Patrick A, Plun-Favreau, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762952/
https://www.ncbi.nlm.nih.gov/pubmed/36074904
http://dx.doi.org/10.1093/brain/awac325

Ejemplares similares

Ejemplares similares