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Dual Roles of Lactate in EGFR-TKI-Resistant Lung Cancer by Targeting GPR81 and MCT1

Lactate is critical in modeling tumor microenvironment causing chemotherapy resistance; however, the role of lactate in tyrosine kinase inhibitor (TKI) resistance has not been fully known. The aim of this study was to evaluate whether lactate could mediate TKI resistance through GPR81 and MCT1 in no...

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Detalles Bibliográficos
Autores principales:	Ma, Ruishuang, Li, Xin, Gong, Shengping, Ge, Xiaoqin, Zhu, Ting, Ge, Xiaoxu, Weng, Lijuan, Tao, Qingsong, Guo, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763017/ https://www.ncbi.nlm.nih.gov/pubmed/36545125 http://dx.doi.org/10.1155/2022/3425841

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