Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

Impairment of translation can lead to collisions of ribosomes, which constitute an activation platform for several ribosomal stress-surveillance pathways. Among these is the ribotoxic stress response (RSR), where ribosomal sensing by the MAP3K ZAKα leads to activation of p38 and JNK kinases. Despite...

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Detalles Bibliográficos
Autores principales: Snieckute, Goda, Genzor, Aitana Victoria, Vind, Anna Constance, Ryder, Laura, Stoneley, Mark, Chamois, Sébastien, Dreos, René, Nordgaard, Cathrine, Sass, Frederike, Blasius, Melanie, López, Aida Rodríguez, Brynjólfsdóttir, Sólveig Hlín, Andersen, Kasper Langebjerg, Willis, Anne E., Frankel, Lisa B., Poulsen, Steen Seier, Gatfield, David, Gerhart-Hines, Zachary, Clemmensen, Christoffer, Bekker-Jensen, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763090/
https://www.ncbi.nlm.nih.gov/pubmed/36384144
http://dx.doi.org/10.1016/j.cmet.2022.10.011

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