Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia

Schizophrenia is a polygenic psychiatric disorder with limited understanding about the mechanistic changes in gene expression regulation. To elucidate on this, we integrate interindividual variability of regulatory activity (ChIP-sequencing for H3K27ac histone mark) with gene expression and genotype...

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Detalles Bibliográficos
Autores principales: Alver, Maris, Lykoskoufis, Nikolaos, Ramisch, Anna, Dermitzakis, Emmanouil T., Ongen, Halit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763101/
https://www.ncbi.nlm.nih.gov/pubmed/36114277
http://dx.doi.org/10.1038/s41380-022-01768-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763101/
https://www.ncbi.nlm.nih.gov/pubmed/36114277
http://dx.doi.org/10.1038/s41380-022-01768-4

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