Cargando…
Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia
Schizophrenia is a polygenic psychiatric disorder with limited understanding about the mechanistic changes in gene expression regulation. To elucidate on this, we integrate interindividual variability of regulatory activity (ChIP-sequencing for H3K27ac histone mark) with gene expression and genotype...
Autores principales: | Alver, Maris, Lykoskoufis, Nikolaos, Ramisch, Anna, Dermitzakis, Emmanouil T., Ongen, Halit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763101/ https://www.ncbi.nlm.nih.gov/pubmed/36114277 http://dx.doi.org/10.1038/s41380-022-01768-4 |
Ejemplares similares
-
Alternative Splicing QTLs in European and African Populations
por: Ongen, Halit, et al.
Publicado: (2015) -
Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity
por: Avalos, Diana, et al.
Publicado: (2023) -
A complete tool set for molecular QTL discovery and analysis
por: Delaneau, Olivier, et al.
Publicado: (2017) -
Fast and efficient QTL mapper for thousands of molecular phenotypes
por: Ongen, Halit, et al.
Publicado: (2016) -
Regulation of HLA class I expression by non-coding gene variations
por: Bettens, Florence, et al.
Publicado: (2022)