Cargando…

Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer—a double-blind, randomized placebo-controlled clinical multicenter phase IV trial

PURPOSE: Insomnia is frequent in patients with advanced cancer, and a variety of pharmacological agents is used to treat this condition. Still, few clinical trials have investigated the effectiveness of pharmacological sleep therapies in this patient group. We aimed to study the short-term effective...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jakobsen, Gunnhild, Sjue, Karin, Paulsen, Ørnulf, Kaasa, Stein, Hjermstad, Marianne Jensen, Klepstad, Pål
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763131/ https://www.ncbi.nlm.nih.gov/pubmed/36534165 http://dx.doi.org/10.1007/s00520-022-07537-x

Ejemplares similares

Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial
por: Jakobsen, Gunnhild, et al.
Publicado: (2018)

The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
por: Jakobsen, Gunnhild, et al.
Publicado: (2020)

An Update on Prevalence, Assessment, and Risk Factors for Sleep Disturbances in Patients with Advanced Cancer—Implications for Health Care Providers and Clinical Research
por: Jakobsen, Gunnhild, et al.
Publicado: (2022)

Eszopiclone versus zopiclone in the treatment of insomnia
por: Pinto, Luciano Ribeiro, et al.
Publicado: (2016)

Inadequate symptom control in advanced cancer patients across Europe
por: Laugsand, Eivor A., et al.
Publicado: (2010)

The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer
por: Paulsen, Ørnulf, et al.
Publicado: (2017)

Pain Intensity Factors Changing Breakthrough Pain Prevalence in Patients with Advanced Cancer: A Secondary Analysis of a Cross-Sectional Observational International Study
por: Løhre, Erik Torbjørn, et al.
Publicado: (2018)

Residual effects of zopiclone 7.5 mg on highway driving performance in insomnia patients and healthy controls: a placebo controlled crossover study
por: Leufkens, T. R. M., et al.
Publicado: (2014)

An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer
por: Dolan, Ross D., et al.
Publicado: (2019)

Parenteral Formulation of Zopiclone
por: Swamy, P. V., et al.
Publicado: (2008)

P018 The effects of zopiclone on sleep spindles in obstructive sleep apnea: A randomized placebo-controlled trial
por: Carter, S, et al.
Publicado: (2021)

Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study
por: Bye, Asta, et al.
Publicado: (2022)

Integration of palliative care in oncology—the intersection of cultures and perspectives of oncology and palliative care
por: Lundeby, Tonje, et al.
Publicado: (2022)

Oral nicotinamide mononucleotide (NMN) to treat chronic insomnia: protocol for the multicenter, randomized, double-blinded, placebo-controlled trial
por: Gao, Xiangyang, et al.
Publicado: (2023)

Health care providers underestimate symptom intensities of cancer patients: A multicenter European study
por: Laugsand, Eivor A, et al.
Publicado: (2010)

Barriers to and facilitators for implementing quality improvements in palliative care – results from a qualitative interview study in Norway
por: Sommerbakk, Ragni, et al.
Publicado: (2016)

Efficacy and Safety of Pulse Magnetic Therapy System in Insomnia Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
por: Liao, Jiwu, et al.
Publicado: (2023)

Can cancer patients assess the influence of pain on functions? A randomised, controlled study of the pain interference items in the Brief Pain Inventory
por: Stenseth, Guri, et al.
Publicado: (2007)

Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil
por: Jordahn, Zarah, et al.
Publicado: (2016)

Better than sham? A double-blind placebo-controlled neurofeedback study in primary insomnia
por: Schabus, Manuel, et al.
Publicado: (2017)

Attentional bias modification training for insomnia: A double-blind placebo controlled randomized trial
por: Lancee, Jaap, et al.
Publicado: (2017)

Using Process Indicators to Monitor Documentation of Patient-Centred Variables in an Integrated Oncology and Palliative Care Pathway—Results from a Cluster Randomized Trial
por: Hjermstad, Marianne Jensen, et al.
Publicado: (2021)

Antibiotic Therapy in Integrated Oncology and Palliative Cancer Care: An Observational Study
por: Moen, Martine Kjølberg, et al.
Publicado: (2022)

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial
por: Abbasi, Behnood, et al.
Publicado: (2012)

Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
por: Foroughinia, Saeedeh, et al.
Publicado: (2020)

Acupuncture treatment of hypertension with insomnia: A protocol for randomized, double-blind, placebo controlled trial research
por: Zhu, Xun, et al.
Publicado: (2022)

Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl
por: Barratt, Daniel T., et al.
Publicado: (2015)

Multicenter, randomized, double‐blinded, placebo‐controlled study of rabacfosadine in dogs with lymphoma
por: Weishaar, Kristen M., et al.
Publicado: (2021)

Symptoms in the general Norwegian adult population - prevalence and associated factors
por: Krogstad, Hilde, et al.
Publicado: (2020)

Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases
por: Løhre, Erik Torbjørn, et al.
Publicado: (2023)

BP-C1 in the treatment of patients with stage IV breast cancer: a randomized, double-blind, placebo-controlled multicenter study and an additional open-label treatment phase
por: Larsen, Stig, et al.
Publicado: (2014)

Naltrexone during pain conditioning: A double-blind placebo-controlled experimental trial
por: Pontén, Moa, et al.
Publicado: (2020)

Preparation, Characterization and in vivo Evaluation of Parenteral Sustained Release Microsphere Formulation of Zopiclone
por: Swapna, N, et al.
Publicado: (2010)

The Efficacy of Oral Melatonin in Improving Sleep in Cancer Patients with Insomnia: A Randomized Double-Blind Placebo-Controlled Study
por: Kurdi, Madhuri S, et al.
Publicado: (2016)

Clinical Efficacy of the Chinese Herbal Medicine Shumian Capsule for Insomnia: A Randomized, Double-Blind, Placebo-Controlled Trial
por: Chen, Suzhen, et al.
Publicado: (2022)

Genetic variation in the Catechol-O-Methyltransferase (COMT) gene and morphine requirements in cancer patients with pain
por: Rakvåg, Trude T, et al.
Publicado: (2008)

Genetic variation and cognitive dysfunction in opioid‐treated patients with cancer
por: Kurita, Geana Paula, et al.
Publicado: (2016)

Effects of Omeprazole on Sleep Disturbance: Randomized Multicenter Double-Blind Placebo-Controlled Trial
por: Aimi, Masahito, et al.
Publicado: (2014)

PALLiON – PALLiative care Integrated in ONcology: study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care
por: Hjermstad, Marianne Jensen, et al.
Publicado: (2020)

Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
por: Verkissen, Mariëtte N., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oq1hpl5ml1s9prlkpj932ligi5