ePHex: a phase 3, double-blind, placebo-controlled, randomized study to evaluate long-term efficacy and safety of Oxalobacter formigenes in patients with primary hyperoxaluria

BACKGROUND: Primary hyperoxalurias (PHs) are rare genetic diseases that increase the endogenous level of oxalate, a waste metabolite excreted predominantly by the kidneys and also the gut. Treatments aim to improve oxalate excretion, or reduce oxalate generation, to prevent kidney function deteriora...

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Detalles Bibliográficos
Autores principales: Ariceta, Gema, Collard, Laure, Abroug, Saoussen, Moochhala, Shabbir H., Gould, Edward, Boussetta, Abir, Ben Hmida, Mohamed, De, Sudarsana, Hunley, Tracy E., Jarraya, Faical, Fraga, Gloria, Banos, Ana, Lindner, Elisabeth, Dehmel, Bastian, Schalk, Gesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763141/
https://www.ncbi.nlm.nih.gov/pubmed/35552824
http://dx.doi.org/10.1007/s00467-022-05591-5

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