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Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis
OBJECTIVE: Ulcerative colitis (UC) is a chronic, debilitating immune-mediated disease driven by disturbed mucosal homeostasis, with an excess of intestinal effector T cells and an insufficient expansion of mucosal regulatory T cells (Tregs). We here report on the successful adoptive transfer of auto...
Autores principales: | Voskens, Caroline, Stoica, Diane, Rosenberg, Marita, Vitali, Francesco, Zundler, Sebastian, Ganslmayer, Marion, Knott, Heike, Wiesinger, Manuel, Wunder, Jutta, Kummer, Mirko, Siegmund, Britta, Schnoy, Elisabeth, Rath, Timo, Hartmann, Arndt, Hackstein, Holger, Schuler-Thurner, Beatrice, Berking, Carola, Schuler, Gerold, Atreya, Raja, Neurath, Markus F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763232/ https://www.ncbi.nlm.nih.gov/pubmed/35428657 http://dx.doi.org/10.1136/gutjnl-2022-327075 |
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