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Voluntary wheel running alters markers of amyloid-beta precursor protein processing in an ovarian hormone depleted model
INTRODUCTION: Aberrant cleavage of the transmembrane protein, amyloid-beta precursor protein (ABPP), results in the overproduction of amyloid-beta (AB) peptides which can form senile plaques in the brain. These plaques can get lodged within synapses and disrupt neuronal communication ultimately lead...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763310/ https://www.ncbi.nlm.nih.gov/pubmed/36561562 http://dx.doi.org/10.3389/fendo.2022.1069404 |