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Voluntary wheel running alters markers of amyloid-beta precursor protein processing in an ovarian hormone depleted model

INTRODUCTION: Aberrant cleavage of the transmembrane protein, amyloid-beta precursor protein (ABPP), results in the overproduction of amyloid-beta (AB) peptides which can form senile plaques in the brain. These plaques can get lodged within synapses and disrupt neuronal communication ultimately lead...

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Detalles Bibliográficos
Autores principales:	Mohammad, Ahmad, Finch, Michael S., Sweezey-Munroe, Jacob, MacPherson, Rebecca E. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763310/ https://www.ncbi.nlm.nih.gov/pubmed/36561562 http://dx.doi.org/10.3389/fendo.2022.1069404

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