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Contrast-induced acute kidney injury and its contemporary prevention
The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763312/ https://www.ncbi.nlm.nih.gov/pubmed/36561776 http://dx.doi.org/10.3389/fcvm.2022.1073072 |
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author | Sůva, Marek Kala, Petr Poloczek, Martin Kaňovský, Jan Štípal, Roman Radvan, Martin Hlasensky, Jiří Hudec, Martin Brázdil, Vojtěch Řehořová, Jitka |
author_facet | Sůva, Marek Kala, Petr Poloczek, Martin Kaňovský, Jan Štípal, Roman Radvan, Martin Hlasensky, Jiří Hudec, Martin Brázdil, Vojtěch Řehořová, Jitka |
author_sort | Sůva, Marek |
collection | PubMed |
description | The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney injury (CI-AKI). At present, effective therapy of CI-AKI is rather limited. Effective prevention of CI-AKI therefore becomes crucially important. This review presents an in-depth discussion of CI-AKI incidence, pathogenesis, risk prediction, current preventive strategies, and novel treatment possibilities. The review also discusses the difference between CI-AKI incidence following intraarterial and intravenous CM administration. Factors contributing to the development of CI-AKI are considered in conjunction with the mechanism of acute kidney damage. The need for ultimate risk estimation and the prediction of CI-AKI is stressed. Possibilities of CI-AKI prevention is evaluated within the spectrum of existing preventive measures aimed at reducing kidney injury. In particular, the review discusses intravenous hydration regimes and pre-treatment with statins and N-acetylcysteine. The review further focuses on emerging alternative imaging technologies, alternative intravascular diagnostic and interventional procedures, and new methods for intravenous hydration guidance; it discusses the applicability of those techniques in complex procedures and their feasibility in current practise. We put emphasis on contemporary interventional cardiology imaging methods, with a brief discussion of CI-AKI in non-vascular and non-cardiologic imaging and interventional studies. |
format | Online Article Text |
id | pubmed-9763312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97633122022-12-21 Contrast-induced acute kidney injury and its contemporary prevention Sůva, Marek Kala, Petr Poloczek, Martin Kaňovský, Jan Štípal, Roman Radvan, Martin Hlasensky, Jiří Hudec, Martin Brázdil, Vojtěch Řehořová, Jitka Front Cardiovasc Med Cardiovascular Medicine The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney injury (CI-AKI). At present, effective therapy of CI-AKI is rather limited. Effective prevention of CI-AKI therefore becomes crucially important. This review presents an in-depth discussion of CI-AKI incidence, pathogenesis, risk prediction, current preventive strategies, and novel treatment possibilities. The review also discusses the difference between CI-AKI incidence following intraarterial and intravenous CM administration. Factors contributing to the development of CI-AKI are considered in conjunction with the mechanism of acute kidney damage. The need for ultimate risk estimation and the prediction of CI-AKI is stressed. Possibilities of CI-AKI prevention is evaluated within the spectrum of existing preventive measures aimed at reducing kidney injury. In particular, the review discusses intravenous hydration regimes and pre-treatment with statins and N-acetylcysteine. The review further focuses on emerging alternative imaging technologies, alternative intravascular diagnostic and interventional procedures, and new methods for intravenous hydration guidance; it discusses the applicability of those techniques in complex procedures and their feasibility in current practise. We put emphasis on contemporary interventional cardiology imaging methods, with a brief discussion of CI-AKI in non-vascular and non-cardiologic imaging and interventional studies. Frontiers Media S.A. 2022-12-06 /pmc/articles/PMC9763312/ /pubmed/36561776 http://dx.doi.org/10.3389/fcvm.2022.1073072 Text en Copyright © 2022 Sůva, Kala, Poloczek, Kaňovský, Štípal, Radvan, Hlasensky, Hudec, Brázdil and Řehořová. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Sůva, Marek Kala, Petr Poloczek, Martin Kaňovský, Jan Štípal, Roman Radvan, Martin Hlasensky, Jiří Hudec, Martin Brázdil, Vojtěch Řehořová, Jitka Contrast-induced acute kidney injury and its contemporary prevention |
title | Contrast-induced acute kidney injury and its contemporary prevention |
title_full | Contrast-induced acute kidney injury and its contemporary prevention |
title_fullStr | Contrast-induced acute kidney injury and its contemporary prevention |
title_full_unstemmed | Contrast-induced acute kidney injury and its contemporary prevention |
title_short | Contrast-induced acute kidney injury and its contemporary prevention |
title_sort | contrast-induced acute kidney injury and its contemporary prevention |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763312/ https://www.ncbi.nlm.nih.gov/pubmed/36561776 http://dx.doi.org/10.3389/fcvm.2022.1073072 |
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