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Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles
Acutely silencing specific neurons informs about their functional roles in circuits and behavior. Existing optogenetic silencers include ion pumps, channels, metabotropic receptors, and tools that damage the neurotransmitter release machinery. While the former hyperpolarize the cell, alter ionic gra...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763335/ https://www.ncbi.nlm.nih.gov/pubmed/36535932 http://dx.doi.org/10.1038/s41467-022-35324-z |