Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles

Acutely silencing specific neurons informs about their functional roles in circuits and behavior. Existing optogenetic silencers include ion pumps, channels, metabotropic receptors, and tools that damage the neurotransmitter release machinery. While the former hyperpolarize the cell, alter ionic gra...

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Detalles Bibliográficos
Autores principales: Vettkötter, Dennis, Schneider, Martin, Goulden, Brady D., Dill, Holger, Liewald, Jana, Zeiler, Sandra, Guldan, Julia, Ateş, Yilmaz Arda, Watanabe, Shigeki, Gottschalk, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763335/
https://www.ncbi.nlm.nih.gov/pubmed/36535932
http://dx.doi.org/10.1038/s41467-022-35324-z

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