Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein

Parkinson´s disease (PD) pathology progresses throughout the nervous system. Whereas motor symptoms are always present, there is a high variability in the prevalence of non-motor symptoms. It has been postulated that the progression of the pathology is based on a prion-like disease mechanism partly...

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Detalles Bibliográficos
Autores principales: Dening, Yanina, Straßl, Theresa, Ruf, Viktoria, Dirscherl, Petra, Chovsepian, Alexandra, Stievenard, Alicia, Khairnar, Amit, Schmidt, Felix, Giesert, Florian, Herms, Jochen, Levin, Johannes, Dieterich, Marianne, Falkai, Peter, Weisenhorn, Daniela Vogt, Wurst, Wolfgang, Giese, Armin, Pan-Montojo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763379/
https://www.ncbi.nlm.nih.gov/pubmed/36535974
http://dx.doi.org/10.1038/s41598-022-25790-2

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