DNA methylation and gene expression analysis in adipose tissue to identify new loci associated with T2D development in obesity

BACKGROUND: Obesity is accompanied by excess adipose fat storage, which may lead to adipose dysfunction, insulin resistance, and type 2 diabetes (T2D). Currently, the tendency to develop T2D in obesity cannot be explained by genetic variation alone—epigenetic mechanisms, such as DNA methylation, mig...

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Detalles Bibliográficos
Autores principales: Baca, Paulina, Barajas-Olmos, Francisco, Mirzaeicheshmeh, Elaheh, Zerrweck, Carlos, Guilbert, Lizbeth, Sánchez, Ernesto Carlos, Flores-Huacuja, Marlen, Villafán, Rafael, Martínez-Hernández, Angélica, García-Ortiz, Humberto, Contreras-Cubas, Cecilia, Centeno-Cruz, Federico, Orozco, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763387/
https://www.ncbi.nlm.nih.gov/pubmed/36535927
http://dx.doi.org/10.1038/s41387-022-00228-w

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