Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease

The imaging appearances of the skeletal system have been well documented in sickle cell disease (SCD) but there is limited information about the impact of SCD treatments on skeletal abnormalities. We present two patients with SCD maintained on long-term erythrocytapheresis and the changes to their s...

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Autores principales: Popham, Emily, Moeller, Karen, Raj, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763515/
https://www.ncbi.nlm.nih.gov/pubmed/36385464
http://dx.doi.org/10.1007/s44228-022-00022-6
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author Popham, Emily
Moeller, Karen
Raj, Ashok
author_facet Popham, Emily
Moeller, Karen
Raj, Ashok
author_sort Popham, Emily
collection PubMed
description The imaging appearances of the skeletal system have been well documented in sickle cell disease (SCD) but there is limited information about the impact of SCD treatments on skeletal abnormalities. We present two patients with SCD maintained on long-term erythrocytapheresis and the changes to their skeletal abnormalities on neuroimaging with this treatment. We observed a reversal of the bone marrow conversion process and the skull appearance was age appropriate without any radiographic findings of iron overload in the patients.
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spelling pubmed-97635152023-01-04 Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease Popham, Emily Moeller, Karen Raj, Ashok Clin Hematol Int Research Article The imaging appearances of the skeletal system have been well documented in sickle cell disease (SCD) but there is limited information about the impact of SCD treatments on skeletal abnormalities. We present two patients with SCD maintained on long-term erythrocytapheresis and the changes to their skeletal abnormalities on neuroimaging with this treatment. We observed a reversal of the bone marrow conversion process and the skull appearance was age appropriate without any radiographic findings of iron overload in the patients. Springer Netherlands 2022-11-16 /pmc/articles/PMC9763515/ /pubmed/36385464 http://dx.doi.org/10.1007/s44228-022-00022-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Popham, Emily
Moeller, Karen
Raj, Ashok
Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title_full Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title_fullStr Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title_full_unstemmed Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title_short Effects of Erythrocytapheresis Procedures on Delayed Bone Marrow Conversion in Sickle Cell Disease
title_sort effects of erythrocytapheresis procedures on delayed bone marrow conversion in sickle cell disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763515/
https://www.ncbi.nlm.nih.gov/pubmed/36385464
http://dx.doi.org/10.1007/s44228-022-00022-6
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AT rajashok effectsoferythrocytapheresisproceduresondelayedbonemarrowconversioninsicklecelldisease

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