Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3‐mediated N6‐methyladenosine modification of ICAM2 mRNA in fibroblast‐like synoviocytes

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease. We previously revealed that the natural compound artemisitene (ATT) exhibits excellent broad anticancer activities without toxicity on normal tissues. Nevertheless, the effect of ATT on RA is undiscovered. Herein, we aim to study...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Lin, Xian, He, Juan, Liu, Dandan, He, Lianhua, Zhang, Miaomiao, Luan, Huijie, Hu, Yiping, Tao, Cheng, Wang, Qingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763537/
https://www.ncbi.nlm.nih.gov/pubmed/36536495
http://dx.doi.org/10.1002/ctm2.1148

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