Analyzing the postulated inhibitory effect of Manumycin A on farnesyltransferase

Manumycin A is postulated to be a specific inhibitor against the farnesyltransferase (FTase) since this effect has been shown in 1993 for yeast FTase. Since then, plenty of studies investigated Manumycin A in human cells as well as in model organisms like Caenorhabditis elegans. Some studies pointed...

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Detalles Bibliográficos
Autores principales: Hagemann, Anna, Altrogge, Philipp Klemens, Kehrenberg, Miriam Caroline Alice, Diehl, Daniel, Jung, Dominik, Weber, Lea, Bachmann, Hagen Sjard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763582/
https://www.ncbi.nlm.nih.gov/pubmed/36561140
http://dx.doi.org/10.3389/fchem.2022.967947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763582/
https://www.ncbi.nlm.nih.gov/pubmed/36561140
http://dx.doi.org/10.3389/fchem.2022.967947

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