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Analyzing the postulated inhibitory effect of Manumycin A on farnesyltransferase
Manumycin A is postulated to be a specific inhibitor against the farnesyltransferase (FTase) since this effect has been shown in 1993 for yeast FTase. Since then, plenty of studies investigated Manumycin A in human cells as well as in model organisms like Caenorhabditis elegans. Some studies pointed...
Autores principales: | Hagemann, Anna, Altrogge, Philipp Klemens, Kehrenberg, Miriam Caroline Alice, Diehl, Daniel, Jung, Dominik, Weber, Lea, Bachmann, Hagen Sjard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763582/ https://www.ncbi.nlm.nih.gov/pubmed/36561140 http://dx.doi.org/10.3389/fchem.2022.967947 |
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