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Pediatric pulmonary actinomycosis: A misdiagnosed case report

BACKGROUND: Pulmonary actinomycosis is an uncommon kind of bacterial illness caused by actinomycetes, involving the chest wall in extraordinarily rare cases. Due to non-specific clinical signs and perplexing radiological characteristics, this kind of pulmonary actinomycosis is frequently misinterpre...

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Autores principales: Yilin, Zhao, Xinyi, Liu, Longwei, Sun, Hongwu, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763604/
https://www.ncbi.nlm.nih.gov/pubmed/36561486
http://dx.doi.org/10.3389/fped.2022.955554
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author Yilin, Zhao
Xinyi, Liu
Longwei, Sun
Hongwu, Zeng
author_facet Yilin, Zhao
Xinyi, Liu
Longwei, Sun
Hongwu, Zeng
author_sort Yilin, Zhao
collection PubMed
description BACKGROUND: Pulmonary actinomycosis is an uncommon kind of bacterial illness caused by actinomycetes, involving the chest wall in extraordinarily rare cases. Due to non-specific clinical signs and perplexing radiological characteristics, this kind of pulmonary actinomycosis is frequently misinterpreted as a malignant tumor or lung abscess. CASE PRESENTATION: An 11-year-old child presented with a palpable lump on his left chest and periodic chest discomfort. An irregular soft-tissue mass in the left upper zone with bony destruction was first identified as a malignant small round cell tumor (MSRCT) known as an Askin tumor on post-contrast CT. However, pathological biopsy of the pulmonary lesion through the chest wall revealed actinomycosis. CONCLUSION: Pulmonary actinomycosis is an uncommon bacterial illness that has a variety of clinical manifestations, particularly in young patients. A chest lump with nearby “lace-like” rib bone destruction was the distinguishing characteristic of our case. For appropriate treatment and diagnosis, infection with actinomycosis should be considered when observing a similar chest lump. Pathological biopsy, as a valuable diagnostic tool, can help to distinguish between infectious diseases and thoracic tumors. The pathological manifestations of actinomycosis are characterized by inflammatory lesions that range from purulent to granuloma-like inflammatory processes, and second-generation sequencing of alveolar lavage fluid can help to confirm pathogens.
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spelling pubmed-97636042022-12-21 Pediatric pulmonary actinomycosis: A misdiagnosed case report Yilin, Zhao Xinyi, Liu Longwei, Sun Hongwu, Zeng Front Pediatr Pediatrics BACKGROUND: Pulmonary actinomycosis is an uncommon kind of bacterial illness caused by actinomycetes, involving the chest wall in extraordinarily rare cases. Due to non-specific clinical signs and perplexing radiological characteristics, this kind of pulmonary actinomycosis is frequently misinterpreted as a malignant tumor or lung abscess. CASE PRESENTATION: An 11-year-old child presented with a palpable lump on his left chest and periodic chest discomfort. An irregular soft-tissue mass in the left upper zone with bony destruction was first identified as a malignant small round cell tumor (MSRCT) known as an Askin tumor on post-contrast CT. However, pathological biopsy of the pulmonary lesion through the chest wall revealed actinomycosis. CONCLUSION: Pulmonary actinomycosis is an uncommon bacterial illness that has a variety of clinical manifestations, particularly in young patients. A chest lump with nearby “lace-like” rib bone destruction was the distinguishing characteristic of our case. For appropriate treatment and diagnosis, infection with actinomycosis should be considered when observing a similar chest lump. Pathological biopsy, as a valuable diagnostic tool, can help to distinguish between infectious diseases and thoracic tumors. The pathological manifestations of actinomycosis are characterized by inflammatory lesions that range from purulent to granuloma-like inflammatory processes, and second-generation sequencing of alveolar lavage fluid can help to confirm pathogens. Frontiers Media S.A. 2022-12-06 /pmc/articles/PMC9763604/ /pubmed/36561486 http://dx.doi.org/10.3389/fped.2022.955554 Text en © 2022 Yilin, Xinyi, Longwei and Hongwu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Yilin, Zhao
Xinyi, Liu
Longwei, Sun
Hongwu, Zeng
Pediatric pulmonary actinomycosis: A misdiagnosed case report
title Pediatric pulmonary actinomycosis: A misdiagnosed case report
title_full Pediatric pulmonary actinomycosis: A misdiagnosed case report
title_fullStr Pediatric pulmonary actinomycosis: A misdiagnosed case report
title_full_unstemmed Pediatric pulmonary actinomycosis: A misdiagnosed case report
title_short Pediatric pulmonary actinomycosis: A misdiagnosed case report
title_sort pediatric pulmonary actinomycosis: a misdiagnosed case report
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763604/
https://www.ncbi.nlm.nih.gov/pubmed/36561486
http://dx.doi.org/10.3389/fped.2022.955554
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