On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w

Organisms must either synthesize or assimilate essential organic compounds to survive. The homocysteine synthase Met15 has been considered essential for inorganic sulfur assimilation in yeast since its discovery in the 1970s. As a result, MET15 has served as a genetic marker for hundreds of experime...

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Detalles Bibliográficos
Autores principales: Van Oss, S. Branden, Parikh, Saurin Bipin, Castilho Coelho, Nelson, Wacholder, Aaron, Belashov, Ivan, Zdancewicz, Sara, Michaca, Manuel, Xu, Jiazhen, Kang, Yun Pyo, Ward, Nathan P., Yoon, Sang Jun, McCourt, Katherine M., McKee, Jake, Ideker, Trey, VanDemark, Andrew P., DeNicola, Gina M., Carvunis, Anne-Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763685/
https://www.ncbi.nlm.nih.gov/pubmed/36379252
http://dx.doi.org/10.1016/j.jbc.2022.102697

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