Cargando…

Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes

Neutrophil and airway epithelial cell interactions are critical in the inflammatory response to viral infections including respiratory syncytial virus, Sendai virus, and SARS-CoV-2. Airway epithelial cell dysfunction during viral infections is likely mediated by the interaction of virus and recruite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shakya, Shubha, Pyles, Kelly D., Albert, Carolyn J., Patel, Rakesh P., McCommis, Kyle S., Ford, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763693/ https://www.ncbi.nlm.nih.gov/pubmed/36508858 http://dx.doi.org/10.1016/j.redox.2022.102557

Ejemplares similares

Endothelial Cell Protein Targeting by Myeloperoxidase-Derived 2-Chlorofatty Aldehyde
por: Shakya, Shubha, et al.
Publicado: (2022)

2-Chlorofatty Aldehyde Elicits Endothelial Cell Activation
por: McHowat, Jane, et al.
Publicado: (2020)

Characterization of N-Acetyl Cysteine Adducts with Exogenous and Neutrophil-Derived 2-Chlorofatty Aldehyde
por: Shakya, Shubha, et al.
Publicado: (2023)

Identification of novel neutrophil very long chain plasmalogen molecular species and their myeloperoxidase mediated oxidation products in human sepsis
por: Amunugama, Kaushalya, et al.
Publicado: (2021)

Fluorescent probes for monitoring myeloperoxidase-derived hypochlorous acid: a comparative study
por: Pierzchała, Karolina, et al.
Publicado: (2022)

Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches
por: Giannoukakis, Nick, et al.
Publicado: (2023)

Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism
por: McCommis, Kyle S., et al.
Publicado: (2018)

The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease
por: McCommis, Kyle S., et al.
Publicado: (2023)

Serum α-chlorofatty acid as a biomarker for baseline subclinical cardiovascular disease in systemic lupus erythematosus
por: Mahieu, MA, et al.
Publicado: (2012)

Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
por: Nybo, Tina, et al.
Publicado: (2018)

A New and Fast-Response Fluorescent Probe for Monitoring Hypochlorous Acid Derived from Myeloperoxidase
por: Świerczyńska, Małgorzata, et al.
Publicado: (2023)

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide
por: Kamm, Dakota R., et al.
Publicado: (2021)

Melatonin Prevents Myeloperoxidase Heme Destruction and the Generation of Free Iron Mediated by Self-Generated Hypochlorous Acid
por: Shaeib, Faten, et al.
Publicado: (2015)

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening
por: Hegazy, Lamees, et al.
Publicado: (2022)

Critical Computational Evidence Regarding the Long-Standing Controversy over the Main Electrophilic Species in Hypochlorous Acid Solution
por: Chen, Ke-Wei, et al.
Publicado: (2022)

Dietary plasmalogen increases erythrocyte membrane plasmalogen in rats
por: Mawatari, Shiro, et al.
Publicado: (2012)

Two Faces of Pioglitazone: Sorting Out the Roles of its PPARγ Binding Versus Mitochondrial Pyruvate Carrier Inhibition Is Not So Simple
por: Yuan, Liyun, et al.
Publicado: (2021)

Enhancing Hepatic MBOAT7 Expression in Mice With Nonalcoholic Steatohepatitis
por: Sharpe, Martin C., et al.
Publicado: (2023)

Electrophilic Aldehyde 4-Hydroxy-2-Nonenal Mediated Signaling and Mitochondrial Dysfunction
por: Sharma, Sudha, et al.
Publicado: (2022)

Plasmalogen Replacement Therapy
por: Bozelli, José Carlos, et al.
Publicado: (2021)

Cardiac‐specific Hexokinase 2 Overexpression Attenuates Hypertrophy by Increasing Pentose Phosphate Pathway Flux
por: McCommis, Kyle S., et al.
Publicado: (2013)

Plasmalogen biosynthesis is spatiotemporally regulated by sensing plasmalogens in the inner leaflet of plasma membranes
por: Honsho, Masanori, et al.
Publicado: (2017)

Plasmalogen Loss in Sepsis and SARS-CoV-2 Infection
por: Pike, Daniel P., et al.
Publicado: (2022)

Plasmalogens and Chronic Inflammatory Diseases
por: Bozelli, José Carlos, et al.
Publicado: (2021)

Plasmalogens in bacteria, sixty years on
por: Goldfine, Howard
Publicado: (2022)

Treating fatty liver disease by modulating mitochondrial pyruvate metabolism
por: Colca, Jerry R., et al.
Publicado: (2017)

Time-Dependent Analysis of Plasmalogens in the Hippocampus of an Alzheimer’s Disease Mouse Model: A Role of Ethanolamine Plasmalogen
por: Azad, Abul Kalam, et al.
Publicado: (2021)

Alcohol, Aldehydes, Adducts and Airways
por: Sapkota, Muna, et al.
Publicado: (2015)

Plasmalogens and Alzheimer’s disease: a review
por: Su, Xiao Q., et al.
Publicado: (2019)

Lymphatic Absorption of Microbial Plasmalogens in Rats
por: Sato, Nana, et al.
Publicado: (2022)

Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens
por: Jackson, David R., et al.
Publicado: (2020)

Targeted Plasmalogen Supplementation: Effects on Blood Plasmalogens, Oxidative Stress Biomarkers, Cognition, and Mobility in Cognitively Impaired Persons
por: Goodenowe, Dayan B., et al.
Publicado: (2022)

Hypochlorous Acid as an Antiseptic in Wounds
por: Newman, E. A. R.
Publicado: (1916)

Hypochlorous Acid: A Review
por: Block, Michael S., et al.
Publicado: (2020)

Controlling the stereochemistry in 2-oxo-aldehyde-derived Ugi adducts through the cinchona alkaloid-promoted electrophilic fluorination
por: Wang, Yuqing, et al.
Publicado: (2020)

Synthesis of 1-Silabenzo[d,e]isochromanes via Electrophilic Aromatic Substitution of Aldehydes Activated by Silylium Ion
por: Arii, Hidekazu, et al.
Publicado: (2022)

Metal‐Free Hydrosilylation of Ketenes with Silicon Electrophiles: Access to Fully Substituted Aldehyde‐Derived Silyl Enol Ethers
por: Roy, Avijit, et al.
Publicado: (2021)

Regulation of Phagocytosis in Macrophages by Membrane Ethanolamine Plasmalogens
por: Rubio, Julio M., et al.
Publicado: (2018)

Plasmalogen loss caused by remodeling deficiency in mitochondria
por: Kimura, Tomohiro, et al.
Publicado: (2019)

Identification of plasmalogens in Bifidobacterium longum, but not in Bifidobacterium animalis
por: Mawatari, Shiro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_54ut6hu1k22h1rhm08sadb8bp5