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Treponema pallidum protein Tp0136 promoting MMPs/TIMPs imbalance via PI3K, MAPK and NF-κB signalling pathways in HDVSMCs

The invasive capability of Treponema. pallidum is central to its infection process. Matrix metalloproteinases (MMPs), which are specifically inhibited by the tissue inhibitors of metalloproteinases (TIMPs), play a pivotal role in promoting pathogenic invasion by destroying tissue barriers within the...

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Detalles Bibliográficos
Autores principales:	Cai, Chun-Xiang, Li, Shu-Lian, Lin, Hui-Ling, Wei, Zi-Han, Xie, Lin, Lin, Li-Rong, Niu, Jian-Jun, Yang, Tian-Ci
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763734/ https://www.ncbi.nlm.nih.gov/pubmed/36561703 http://dx.doi.org/10.1016/j.heliyon.2022.e12065

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