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Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration

Obesity and diabetes are associated with inflammation and altered plasma levels of several metabolites, which may be involved in disease progression. Some metabolites can activate G protein-coupled receptors (GPCRs) expressed on immune cells where they can modulate metabolic inflammation. Here, we f...

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Detalles Bibliográficos
Autores principales: Mikkelsen, Randi Bonke, Arora, Tulika, Trošt, Kajetan, Dmytriyeva, Oksana, Jensen, Sune Kjærsgaard, Meijnikman, Abraham Stijn, Olofsson, Louise Elisabeth, Lappa, Dimitra, Aydin, Ömrüm, Nielsen, Jens, Gerdes, Victor, Moritz, Thomas, van de Laar, Arnold, de Brauw, Maurits, Nieuwdorp, Max, Hjorth, Siv Annegrethe, Schwartz, Thue Walter, Bäckhed, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763857/
https://www.ncbi.nlm.nih.gov/pubmed/36561890
http://dx.doi.org/10.1016/j.isci.2022.105683