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Role of the membrane anchor in the regulation of Lck activity

Theoretical work suggests that collective spatiotemporal behavior of integral membrane proteins should be modulated by boundary lipids sheathing their membrane anchors. Here, we show evidence for this prediction while investigating the mechanism for maintaining a steady amount of the active form of...

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Detalles Bibliográficos
Autores principales: Porciello, Nicla, Cipria, Deborah, Masi, Giulia, Lanz, Anna-Lisa, Milanetti, Edoardo, Grottesi, Alessandro, Howie, Duncan, Cobbold, Steve P., Schermelleh, Lothar, He, Hai-Tao, D’Abramo, Marco, Destainville, Nicolas, Acuto, Oreste, Nika, Konstantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763865/
https://www.ncbi.nlm.nih.gov/pubmed/36372231
http://dx.doi.org/10.1016/j.jbc.2022.102663