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The prevention and treatment of breast cancer- related lymphedema: A review

BACKGROUND: Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed....

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Autores principales: McEvoy, Maureen P., Gomberawalla, Ameer, Smith, Mark, Boccardo, Francesco M., Holmes, Dennis, Djohan, Risal, Thiruchelvam, Paul, Klimberg, Suzanne, Dietz, Jill, Feldman, Sheldon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763870/
https://www.ncbi.nlm.nih.gov/pubmed/36561522
http://dx.doi.org/10.3389/fonc.2022.1062472
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author McEvoy, Maureen P.
Gomberawalla, Ameer
Smith, Mark
Boccardo, Francesco M.
Holmes, Dennis
Djohan, Risal
Thiruchelvam, Paul
Klimberg, Suzanne
Dietz, Jill
Feldman, Sheldon
author_facet McEvoy, Maureen P.
Gomberawalla, Ameer
Smith, Mark
Boccardo, Francesco M.
Holmes, Dennis
Djohan, Risal
Thiruchelvam, Paul
Klimberg, Suzanne
Dietz, Jill
Feldman, Sheldon
author_sort McEvoy, Maureen P.
collection PubMed
description BACKGROUND: Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed. METHODS: The American Society of Breast Surgeons Lymphatic Surgery Working Group conducted a large review of the literature in order to develop guidelines on BCRL prevention and treatment. This was a comprehensive but not systematic review of the literature. This was inclusive of recent randomized controlled trials, meta-analyses, and reviews evaluating the prevention and treatment of BCRL. There were 25 randomized clinical trials, 13 systemic reviews and meta-analyses, and 87 observational studies included. RESULTS: The findings of our review are detailed in the paper, with each guideline being analyzed with the most recent data that the group found evidence of to suggest these recommendations. CONCLUSIONS: Prevention and treatment of BCRL involve a multidisciplinary team. Early detection, before clinically apparent, is crucial to prevent irreversible lymphedema. Awareness of risk factors and appropriate practice adjustments to reduce the risk aids are crucial to decrease the progression of lymphedema. The treatment can be costly, time- consuming, and not always effective, and therefore, the overall goal should be prevention.
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spelling pubmed-97638702022-12-21 The prevention and treatment of breast cancer- related lymphedema: A review McEvoy, Maureen P. Gomberawalla, Ameer Smith, Mark Boccardo, Francesco M. Holmes, Dennis Djohan, Risal Thiruchelvam, Paul Klimberg, Suzanne Dietz, Jill Feldman, Sheldon Front Oncol Oncology BACKGROUND: Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed. METHODS: The American Society of Breast Surgeons Lymphatic Surgery Working Group conducted a large review of the literature in order to develop guidelines on BCRL prevention and treatment. This was a comprehensive but not systematic review of the literature. This was inclusive of recent randomized controlled trials, meta-analyses, and reviews evaluating the prevention and treatment of BCRL. There were 25 randomized clinical trials, 13 systemic reviews and meta-analyses, and 87 observational studies included. RESULTS: The findings of our review are detailed in the paper, with each guideline being analyzed with the most recent data that the group found evidence of to suggest these recommendations. CONCLUSIONS: Prevention and treatment of BCRL involve a multidisciplinary team. Early detection, before clinically apparent, is crucial to prevent irreversible lymphedema. Awareness of risk factors and appropriate practice adjustments to reduce the risk aids are crucial to decrease the progression of lymphedema. The treatment can be costly, time- consuming, and not always effective, and therefore, the overall goal should be prevention. Frontiers Media S.A. 2022-12-06 /pmc/articles/PMC9763870/ /pubmed/36561522 http://dx.doi.org/10.3389/fonc.2022.1062472 Text en Copyright © 2022 McEvoy, Gomberawalla, Smith, Boccardo, Holmes, Djohan, Thiruchelvam, Klimberg, Dietz and Feldman https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
McEvoy, Maureen P.
Gomberawalla, Ameer
Smith, Mark
Boccardo, Francesco M.
Holmes, Dennis
Djohan, Risal
Thiruchelvam, Paul
Klimberg, Suzanne
Dietz, Jill
Feldman, Sheldon
The prevention and treatment of breast cancer- related lymphedema: A review
title The prevention and treatment of breast cancer- related lymphedema: A review
title_full The prevention and treatment of breast cancer- related lymphedema: A review
title_fullStr The prevention and treatment of breast cancer- related lymphedema: A review
title_full_unstemmed The prevention and treatment of breast cancer- related lymphedema: A review
title_short The prevention and treatment of breast cancer- related lymphedema: A review
title_sort prevention and treatment of breast cancer- related lymphedema: a review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763870/
https://www.ncbi.nlm.nih.gov/pubmed/36561522
http://dx.doi.org/10.3389/fonc.2022.1062472
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