Cargando…

Valsartan prevents gefitinib-induced lung inflammation, oxidative stress, and alteration of plasma metabolites in rats

Gefitinib (GEF) is an inhibitor of the epidermal growth factor receptor, linked to higher risk of severe/fatal interstitial lung disease (ILD). This study was performed to determine the protective roles of an angiotensin-II type-1 receptor (AT1R) “valsartan (VAL)” in prevention of lung inflammation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Alanazi, Wael A., Alhamami, Hussain N., Alshamrani, Ali A., Alqahtani, Faleh, Alshammari, Abdulrahman, Alhazzani, Khalid, Alswayyed, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763942/
https://www.ncbi.nlm.nih.gov/pubmed/36561332
http://dx.doi.org/10.1016/j.sjbs.2022.103522