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Optimal predictive probability designs for randomized biomarker-guided oncology trials

INTRODUCTION: Efforts to develop biomarker-targeted anti-cancer therapies have progressed rapidly in recent years. With efforts to expedite regulatory reviews of promising therapies, several targeted cancer therapies have been granted accelerated approval on the basis of evidence acquired in single-...

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Detalles Bibliográficos
Autores principales: Zabor, Emily C., Kaizer, Alexander M., Pennell, Nathan A., Hobbs, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763994/
https://www.ncbi.nlm.nih.gov/pubmed/36561534
http://dx.doi.org/10.3389/fonc.2022.955056

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