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Optimal predictive probability designs for randomized biomarker-guided oncology trials
INTRODUCTION: Efforts to develop biomarker-targeted anti-cancer therapies have progressed rapidly in recent years. With efforts to expedite regulatory reviews of promising therapies, several targeted cancer therapies have been granted accelerated approval on the basis of evidence acquired in single-...
Autores principales: | Zabor, Emily C., Kaizer, Alexander M., Pennell, Nathan A., Hobbs, Brian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763994/ https://www.ncbi.nlm.nih.gov/pubmed/36561534 http://dx.doi.org/10.3389/fonc.2022.955056 |
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