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Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale

Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile. However, among the cutaneous adverse drug reactions due to Ciprofloxacin, toxic epidermal necrolysis occurring along with ch...

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Autores principales: Dhakal, Bishal, Dawadi, Sagun, Khadka, Laxman, Bohara, Sujan, Neupane, Shashank, Ale Magar, Priajan, Pathak, Bishnu Deep, Upadhaya Regmi, Binit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764033/
https://www.ncbi.nlm.nih.gov/pubmed/36545559
http://dx.doi.org/10.1002/ccr3.6766
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author Dhakal, Bishal
Dawadi, Sagun
Khadka, Laxman
Bohara, Sujan
Neupane, Shashank
Ale Magar, Priajan
Pathak, Bishnu Deep
Upadhaya Regmi, Binit
author_facet Dhakal, Bishal
Dawadi, Sagun
Khadka, Laxman
Bohara, Sujan
Neupane, Shashank
Ale Magar, Priajan
Pathak, Bishnu Deep
Upadhaya Regmi, Binit
author_sort Dhakal, Bishal
collection PubMed
description Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile. However, among the cutaneous adverse drug reactions due to Ciprofloxacin, toxic epidermal necrolysis occurring along with cholestatic hepatitis is a rare one. Here, we present a case of a 22‐year‐old male patient who was diagnosed with toxic epidermal necrolysis with cholestatic hepatitis secondary to Ciprofloxacin. Naranjo adverse drug reaction probability scale was used for the causal association.
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spelling pubmed-97640332022-12-20 Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale Dhakal, Bishal Dawadi, Sagun Khadka, Laxman Bohara, Sujan Neupane, Shashank Ale Magar, Priajan Pathak, Bishnu Deep Upadhaya Regmi, Binit Clin Case Rep Case Report Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile. However, among the cutaneous adverse drug reactions due to Ciprofloxacin, toxic epidermal necrolysis occurring along with cholestatic hepatitis is a rare one. Here, we present a case of a 22‐year‐old male patient who was diagnosed with toxic epidermal necrolysis with cholestatic hepatitis secondary to Ciprofloxacin. Naranjo adverse drug reaction probability scale was used for the causal association. John Wiley and Sons Inc. 2022-12-20 /pmc/articles/PMC9764033/ /pubmed/36545559 http://dx.doi.org/10.1002/ccr3.6766 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dhakal, Bishal
Dawadi, Sagun
Khadka, Laxman
Bohara, Sujan
Neupane, Shashank
Ale Magar, Priajan
Pathak, Bishnu Deep
Upadhaya Regmi, Binit
Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title_full Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title_fullStr Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title_full_unstemmed Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title_short Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale
title_sort ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: a case report with literature review and revisit to the naranjo adverse drug reaction probability scale
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764033/
https://www.ncbi.nlm.nih.gov/pubmed/36545559
http://dx.doi.org/10.1002/ccr3.6766
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