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Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer

Chemoresistance remains a major obstacle to successful treatment of triple negative breast cancer (TNBC). Identification of druggable vulnerabilities is an important aim for TNBC therapy. Here, we report that SERCA2 expression correlates with TNBC progression in human patients, which promotes TNBC c...

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Detalles Bibliográficos
Autores principales: Fan, Minmin, Gao, Jian, Zhou, Lin, Xue, Wenwen, Wang, Yixuan, Chen, Jingwei, Li, Wuhao, Yu, Ying, Liu, Bo, Shen, Yan, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764070/
https://www.ncbi.nlm.nih.gov/pubmed/36561988
http://dx.doi.org/10.1016/j.apsb.2022.05.009