Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways

Glioblastoma (GBM) is the most challenging malignant tumor of the central nervous system because of its high morbidity, mortality, and recurrence rate. Currently, mechanisms of GBM are still unclear and there is no effective drug for GBM in the clinic. Therefore, it is urgent to identify new drug ta...

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Detalles Bibliográficos
Autores principales: Li, Wan, Cai, Hongqing, Ren, Liwen, Yang, Yihui, Yang, Hong, Liu, Jinyi, Li, Sha, Zhang, Yizhi, Zheng, Xiangjin, Tan, Wei, Du, Guanhua, Wang, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764134/
https://www.ncbi.nlm.nih.gov/pubmed/36562002
http://dx.doi.org/10.1016/j.apsb.2022.09.012

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