Sub-acute and sub-chronic toxicity assessment of the antimicrobial peptide Dermaseptin B2 on biochemical, haematological and histopathological parameters in BALB/c mice and Albino Wistar rats

BACKGROUND: Dermaseptins (Drs) are peptides found in the skin secretions of a variety of Hylid frogs, particularly those belonging to the Agalychnis and Phyllomedusa families. Dermaseptin B2 (Drs B2), an amphipathic, α-helical polypeptide was reported as the most active of the Dermaseptin B family....

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Detalles Bibliográficos
Autores principales: Abdille, Ahmed A., Kitimu, Shedrack Reuben, Ndubi, Mark M., Kimani, Josephine, Maina, Esther N., Bulimo, Wallace, Gavamukulya, Yahaya, Wamunyokoli, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764173/
https://www.ncbi.nlm.nih.gov/pubmed/36561696
http://dx.doi.org/10.1016/j.heliyon.2022.e12124

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