Cargando…
Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells
Triple-negative breast cancer (TNBC) poses significant challenges for treatment given the lack of targeted therapies and increased probability of relapse. It is pertinent to identify vulnerabilities in TNBC and develop newer treatments. Our prior research demonstrated that transcription factor EB (T...
Autores principales: | Slade, Logan, Biswas, Dipsikha, Kienesberger, Petra C., Pulinilkunnil, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764199/ https://www.ncbi.nlm.nih.gov/pubmed/36372230 http://dx.doi.org/10.1016/j.jbc.2022.102692 |
Ejemplares similares
-
Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity
por: Biswas, Dipsikha, et al.
Publicado: (2021) -
Editorial: Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease
por: Pulinilkunnil, Thomas, et al.
Publicado: (2019) -
Adverse Outcomes in Obese Cardiac Surgery Patients Correlates With Altered Branched-Chain Amino Acid Catabolism in Adipose Tissue and Heart
por: Biswas, Dipsikha, et al.
Publicado: (2020) -
Transcription factor EB (TFEB)-mediated autophagy protects bovine mammary epithelial cells against H(2)O(2)-induced oxidative damage in vitro
por: Sun, Xudong, et al.
Publicado: (2021) -
Effect of (poly)phenol-rich ‘Daux Belan’ apple supplementation on diet-induced obesity and glucose intolerance in C57BL/6NCrl mice
por: Yu, Cindy H. J., et al.
Publicado: (2023)