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Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells

Triple-negative breast cancer (TNBC) poses significant challenges for treatment given the lack of targeted therapies and increased probability of relapse. It is pertinent to identify vulnerabilities in TNBC and develop newer treatments. Our prior research demonstrated that transcription factor EB (T...

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Detalles Bibliográficos
Autores principales: Slade, Logan, Biswas, Dipsikha, Kienesberger, Petra C., Pulinilkunnil, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764199/
https://www.ncbi.nlm.nih.gov/pubmed/36372230
http://dx.doi.org/10.1016/j.jbc.2022.102692

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