Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling

In mammals, the growth and maturation of oocytes within growing follicles largely depends on ovarian granulosa cells (GCs) in response to gonadotropin stimulation. Many signals have been shown to regulate GC proliferation and apoptosis. However, whether the tyrosine phosphatase SHP2 is involved rema...

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Detalles Bibliográficos
Autores principales: Wei, Xiaoli, Zheng, Lanping, Tian, Yingpu, Wang, Haibin, Su, Youqiang, Feng, Gensheng, Wang, Chao, Lu, Zhongxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764209/
https://www.ncbi.nlm.nih.gov/pubmed/36002018
http://dx.doi.org/10.1093/jmcb/mjac048

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